Comprehensive Immunotherapy of Cancer
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The Issels Foundation


The ISSELS FOUNDATION, INC. is a non profit, U.S. tax exempt, charitable organization. The U.S. Internal Revenue Service has designated the ISSELS FOUNDATlON a 501 (c) (3) organization with Federal Tax ID #65-0048212.

In 1987 the foundation was established by llse Marie lssels, whose late husband Josef M. Issels, M.D., was a world renowned leader in the development of a holistic, integrative therapeutic system for the treatment of patients with advanced cancers that had failed to respond to standard approaches. In 1951, Dr. Issels founded the first hospital specializing in the treatment of conventionally "incurable" cancer patients, subsequently treating more than 15,000 patients. Over decades, he demonstrated that conventional anticancer treatments could be successfully combined with unconventional treatments to restore health in even far advanced cases. His use of immunobiological therapies allowed coherent treatment of the cancer patient as a whole person, body and mind, above and beyond efforts to manage the cancer itself. This treatment program became known as the Issels Treatment.

As Dr. Issels' co-worker for four decades, Mrs. Issels was daily confronted by the extreme suffering of terminal cancer patients. She also witnessed the improvement of many of these patients through the Issels Treatment, even though they could not be helped any more by standard managements. A remarkable number of these "incurable" cancer patients achieved long term, complete remissions and were able to lead normal, healthy, cancer-free lives of up to 40 years follow-up.

The modern cancer patient and doctor need to be aware of all available treatment options in order to assemble and employ the most comprehensive and effective therapeutic strategy in a timely manner. All treatments, whether pro-host or anticancer, should be orchestrated from the beginning, to take advantage of the time left, and to insure that steps are taken to correct the underlying conditions which led to development of the disease and which, if not corrected, will lead to recurrence.

Standard cancer medicine has made great strides in its ability to eradicate cancer cells, but has made little if any progress toward correction of the causal factors which lead to production of cancer cells. This is demonstrated by an overall 6% increase in cancer mortality between 1970 and 1994 despite extraordinary advancements in surgery, radiation and chemotherapy (John C. Bailar "Cancer Undefeated," New England Journal of Medicine, May 29, 1997). To date, no significant federal or private funding has been applied to the study of existing immunobiological treatments, despite reports of improved overall outcomes when these treatments are used.

The Issels Foundation is dedicated to research, education, and promotion of the holistic integrative approach to the management of cancer and chronic degenerative diseases, in order to render its beneficial effects more widely available. Donations are welcome and will be used to support this goal. Use the following contact information for donations:

Checks can be mailed to:
Issels Foundation Inc.
8711 E. Pinnacle Peak Road, PMB 101
Scottsdale, Arizona, 85255


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Last updated: 9/5/2007
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