New Blood Test Identifies Which Prostate Cancer Patients Will Respond Favorably to Specific Medications

New Blood Test Identifies Which Prostate Cancer Patients Will Respond Favorably to Specific Medications
New Blood Test Identifies Which Prostate Cancer Patients Will Respond Favorably to Specific Medications

No two cases of cancer are identical, which makes it a challenge to determine what course of cancer treatment will be most effective. Scientists are excited about a new three-in-one blood test that may open the door for precision treatment of advanced prostate cancer.

Three-Pronged Attack on Prostate Cancer

Professor Johann de Bono, leader of the team at the Institute of Cancer Research in London, explained the three functions of the blood test:

• Blood samples are initially checked for the presence of mutated BRCA genes.

• Once treatment begins, DNA in the blood is monitored to determine whether or not the patient is responding.

• In the final step, blood is tested for signs of evolving cancer that is developing a resistance to drugs.

Overcoming Cancer’s Defense Mechanisms

Cancer cells with BRCA mutations use a specific enzyme to repair themselves, making tumors resistant to treatment. Drugs called Parp inhibitors block these enzymes, causing cancer cells to die off. The blood test helps to identify patients who are most likely to respond to Parp inhibitors.

The Institute of Cancer Research’s chief executive, Paul Workman, praised the test as a simple, inexpensive and non-invasive method to develop precision cancer treatment. While the test currently focuses on prostate cancer, Professor de Bono believes it can be adapted to other forms of cancer in the future.

Issels®: Matching the Right Treatment to the Right Patient

Specialized testing has long been a part of our integrative and personalized cancer treatment programs. Contact us to learn more about how Issels® uses cancer vaccines and other immunotherapy treatments to help patients of all ages.

Some Cancers Run in Families – What You Need to Know

Is  Issels Genomic Testing for Personalized Treatment For You
Is Issels Genomic Testing for Personalized Treatment For You

Some families have two or more members who develop the same type of cancer, leading people to believe that it’s inherited. While it’s not passed along like blond hair or brown eyes, there is a genetic element to cancer than can be shared by family members.

How Cell Mutations Give Rise to Cancer

You already know that genes are responsible for certain physical characteristics like height and eye color, but they also contain information that controls cell function. A mutation is an abnormal change that prevents a gene from working properly.

Cancer results from cells that multiply uncontrollably. While the mutations that cause cancer are usually acquired, some inherited mutations affect tumor suppressor genes that act as traffic cops, regulating cell growth and death.

Is It Coincidence or Family Cancer Syndrome?

These inherited gene mutations can lead to family cancer syndrome, in which several members of a family develop similar types of tumors. Telltale factors of family cancer syndrome include:

• Cancer occurring in multiple generations

• Childhood cancer occurring in siblings

• Cancer occurring at unusually young ages

• Two or more types of cancer occurring in a single person

Many times, several diagnoses of cancer within one family can indeed be pure coincidence. They can also be related to family members being exposed to tobacco smoke or other common risk factors.

Genomic Testing for Personalized Cancer Treatment at Issels®

Since our cancer treatment programs target the tumor microenvironment as well as the cancer itself, we use highly specialized testing to address your specific needs. Visit our website to learn more about our cancer treatment that boosts your body’s own immune responses.

American Cancer Society Guidelines for Nutrition and Exercise for Cancer Prevention

Excercise and Healthy Eating for Cancer Prevention
Exercise and Healthy Eating for Cancer Prevention

Have you made it a priority to watch your weight? According to the American Cancer Society (ACS), a healthy diet and physical activity are the most important cancer risk prevention factors after avoiding tobacco.

How much of a difference can nutrition and exercise make? The World Cancer Research Fund estimates that approximately 20 percent of all cancers diagnosed in the United States are related to excess weight and poor eating habits.

Reduce Cancer Risk with Healthy Habits

You may not be able to control your genetic makeup, but you can take steps to stay active and maintain a proper weight. Follow these guidelines offered by the ACS:

• Stay as lean as possible. If you’re overweight, even a modest weight loss can improve your health.

• Get a minimum of 30 minutes of moderate physical activity at least five times a week.

• Limit “screen time” with TVs, computers, video games and other sedentary activities.

• Practice portion control during mealtimes.

• Minimize consumption of red meat and processed meat. Eat at least five half-cup servings of fruits and vegetables each day.

• Avoid refined grain food items, such as white bread and white rice, that have little nutritional value. Opt for barley, brown rice, oatmeal and other whole-grain products.

• Daily alcohol intake should be limited to one drink for women and two drinks for men.

Issels®: Incorporating Good Nutrition in Immunotherapy for Cancer

Our non-toxic, integrative programs include nutritional immunotherapy for cancer treatments to restore balance of vitamins and minerals that promote healthy functioning of the immune system. Contact us for more information about our specialized testing and treatment programs to meet your specific needs.

FDA Quickly Approves New One-of-a-Kind Cancer Treatment

There is New Hope for Cancer Patients.
There is New Hope for Cancer Patients.

Researchers have made a number of significant breakthroughs in cancer treatment, but a recent development has the healthcare community particularly excited. The Food and Drug Administration (FDA) has approved a drug that treats tumors based on a genetic abnormality.

Keytruda: A Landmark in Immunotherapy for Cancer

Pembrolizumab, marketed under the trade name Keytruda, was tested on a trial group of 86 patients. The results were remarkable: 66 patients saw their tumors shrink and stabilize, while the tumors in 18 of them disappeared with no recurrence.

What’s different about Keytruda? It’s the first drug that attacks tumors from a shared genetic profile rather than the actual location of the tumor. A prospective patient first undergoes testing to determine whether he or she is a genetic match for the mutations targeted by Keytruda.

Current and Future Possibilities

At present, Keytruda is approved for treating only select forms of advanced bladder, lung and melanoma tumors. The drug will be effective for approximately four percent of cancer patients, which still equates to tens of thousands of people.

Scientists are encouraged by the possibility of further treatment methods tailored to a patient’s specific genetic profile. This ability would greatly enhance development of more accurate targeting and treatment.

Advanced Immunotherapy for Cancer Treatment from Issels®

Issels® uses genomic testing to determine a patient’s individual treatment needs. We then use the information to tailor a personalized immunotherapy for cancer program including methods such as vaccines and NK cells.

We have helped patients with all forms of cancer achieve long-term remission. Contact us to learn more about why the Issels® difference may be right for you.

UV Exposure and the Skin Cancer Connection

Sun Exposure and Cancer
Sun Exposure and Cancer

Exposure to ultra-violet (UV) rays can have more serious consequences than a painful sunburn. UV rays from both natural and man-made sources can increase risk of developing skin cancer.

How UV Rays Damage Skin

While UV rays come primarily from the sun, they contain more energy than visible light. Man-made sources of UV rays include tanning beds and welding torches.

UV rays are powerful enough to ionize atoms by removing an electron, which is how they cause damage to DNA in body cells. But they don’t have enough energy to penetrate to organs and other internal tissues, which is why their effect is seen mostly on skin.

UV Ray Wavelengths

The three types of UV rays are:

  • UVA rays, which are the weakest of the three and linked more to cosmetic damage such as wrinkles than to skin cancer.
  • UVB rays, which are slightly stronger and the main cause of sunburns and skin cancer.
  • UVC rays, which have the most energy but are prevented from reaching the ground by the ozone layer.

Preventing UV Ray Exposure

A certain amount of sunshine is necessary for good health, but protect yourself by applying sunscreen to exposed parts of your body when you’re outside for extended periods. Avoid peak hours of 11 AM until 4 PM and stay in the shade when possible.

Immunotherapy for Cancer: Restoring the Body’s Natural Defenses

At Issels®, our integrative immunotherapy treatments boost your own immune system’s ability to fight cancer. Contact us for more information to learn how immunotherapy for cancer has helped patients diagnosed with skin cancer, melanoma and other types of tumors.

Coaches vs. Cancer Has Raised $100 Million for Cancer Research

Coaches and Teams Have Raised Millions for Research
Coaches and Teams Have Raised Millions for Research

Actors, athletes and other high-profile people often use their celebrity to help promote awareness of cancer research. One such program is Coaches vs. Cancer, which has raised more than $100 million to support the American Cancer Society (ACS).

Leading the Charge Against Cancer

As with most Americans, basketball coaches across the country have been affected by cancer, either personally or through a loved one. The National Association of Basketball Coaches (NABC) has partnered with the ACS to form Coaches vs. Cancer, a program designed to empower the coaches to participate in the fight against cancer.

Coaches vs. Cancer: The “Battles”

Thanks to their personal and professional experiences and positions of leadership, basketball coaches are in a great position to raise awareness of cancer research among their teams and communities. Some of their creative initiatives have included:

  • In February 2017, their 3-Point Challenge let fans pledge an amount for every successful three-point shot made by their favorite team that month.
  • During Suits and Sneakers Week, coaches across the country wear sneakers on game day to symbolize the role of nutrition and physical activity in reducing cancer risk.
  • Hardwood Heroes is part of March Madness, the NCAA’s popular basketball championship tournament. 2017 marked the second year of this event in which a basketball team made up of cancer survivors took on a team of survivors from last year’s game.

Issels®: The Leader in Immunotherapy for Cancer Treatment

For decades, Issels® has raised the bar on cancer treatment with our non-toxic and integrative immunotherapy programs. Visit our website to read and hear testimonials from patients who have achieved long-term remission.