Category Archives: Immuno-Oncology

Is the Cost of R&D for Cancer Medications Overstated?

Are Costs Overstated for Cancer Research?
Are Costs Overstated for Cancer Medication Research?

Significant research and development (R&D) costs are often the main reason cited for steep prices on cancer treatments. Surprisingly, a study centered on 10 new cancer drugs suggests that these costs may have been greatly overstated.

The True Costs of Cancer Treatment R&D?

Results of the study, which was recently published in JAMA Internal Medicine, determined that the R&D process for a new cancer drug usually spans seven years, with an average total cost between $648 million and $794 million.

On its face, the numbers are huge, but relatively small compared to the yardstick used by pharmaceutical companies. Their measure is the staggering figure of $2.7 billion per drug, which was determined by a Tufts University study in 2016.

Cost vs. Benefit

Even more revealing was the assessment of sales generated by the 10 drugs evaluated in the study. After an average of four years on the market, the drugs had a combined total of $67 billion in revenue, which is seven times more than the aggregate of the R&D costs.

As expected, members of the pharmaceutical industry are taking exception with the report. Dr. J. Leonard Lichtenfeld, deputy chief medical officer of the American Cancer Society, took no official position but felt that the study would prompt wider discussion on the issue.

Integrative Cancer Immunotherapy Programs from Issels®

While cancer immunotherapy is a hot topic in the medical community, Issels® has been successfully using non-toxic treatments such as cancer vaccines for decades. Contact us for more information about our cancer centers in Santa Barbara, CA and Tijuana, Mexico.

Cancer Patients – The Struggle to Understand Clinical Trial Opportunities

Cancer Patients Can Struggle to Understand if a Clinical Trial is Right for Them
Cancer Patients Can Struggle to Understand if a Clinical Trial is Right for Them

Clinical trials are essential for continued development of immunotherapy and other cancer treatment methods. A recent study shows that while cancer patients recognize the importance of clinical trials, they lack the same understanding about the concepts behind the process.

What Is the Public Conception of Clinical Trials?

Oncologist Catherine Kelly of Mater Misericordiae University Hospital in Dublin led a study involving 1,090 cancer patients being treated in centers across Ireland. Kelly presented the results at the September meeting of the European Society of Medical Oncology (ESMO) in Madrid.

Despite the fact that more than 25 percent of the subjects had previously participated in clinical trials, misunderstanding of central concepts was widespread throughout the responses.

  • Nearly three-quarters of those who had never taken part in a clinical trial didn’t understand that the types of treatment are randomly assigned. Surprisingly, this also applied to more than half of the patients who had participated in trials.
  • Most patients didn’t understand the concept of clinical equipoise, in which no one knows which of the treatments being tested is better. With previous clinical trial participants, an astonishing 60 percent believed that their doctor knew which treatment was better.

Why Understanding of Clinical Trials Matters

Results of this study were consistent with those from earlier studies. Kelly pointed out the need for doctors to address these misconceptions that instill fear in patients, preventing them from participating in trials.

Issels®: Cancer Treatment that Meets the Test of Time

At Issels®, our cancer vaccines and other immunotherapy treatments are not trials. Contact us to learn more about our long-standing success with individually tailored cancer treatment protocols.

Immunotherapy and Its Use in Stage 2 and 3 Cancers

There is New Hope for Cancer Patients. Don't Give up!
There is New Hope for Cancer Patients. Don’t Give up!

Immunotherapy drugs have become a valuable weapon in the fight against metastatic cancer, also known as Stage 4. Researchers are discovering that immunotherapy for cancer treatment can also have positive results when used during earlier stages of the disease.

Immunotherapy and Early-Stage Cancer

At the recent European Society for Medical Oncology (ESMO) congress in Madrid, AstraZeneca presented successful trial results for its immuno-oncology drug Imfinzi in treating mid-stage lung cancer. AstraZeneca is considered a latecomer to the I-O field as compared to established companies such as Merck and Bristol-Meyers Squibb.

For their part, Bristol-Meyers produced evidence regarding Opdivo, the company’s widely used late-stage I-O drug. Opdivo has been shown to prevent relapses in melanoma patients when administered immediately post-surgery.

Supplementing Surgery with Immunotherapy

This method of following surgery with cancer treatment is referred to as adjuvant therapy. With the success of Opdivo, a number of trials are being conducted on adjuvant therapy using I-O drugs with a range of cancer types. Some trials are even focusing on neoadjuvant, or pre-surgery, treatment for breast, neck and head cancers.

What’s Next?

If the trend of early-stage immunotherapy treatment continues, early detection becomes even more important than ever. According to Pascal Soriot, CEO of AstraZeneca, effective early treatment is a powerful incentive for increased use of screening methods.

Non-Toxic Immunotherapy Programs from Issels®

Our cancer vaccines and other non-toxic, personally tailored immunotherapy treatment programs have resulted in long-term remission for patients with all types of therapy-resistant cancers. Contact us for more information about Issels®, the leader in immunotherapy for cancer treatment.

What Can I Expect at the Issels Mexico In-Patient Hospital?

Do You Have Questions About What to Expect If You Come to Issels?
Do You Have Questions About What to Expect If You Come to Issels?

Cancer treatment is stressful and trying under the best of conditions. A first-class facility and caring staff can make a big difference in your peace of mind. Here’s an actual patient testimonial about her reassuring experience at our Issels® Mexico immunotherapy for cancer in-patient hospital.

“One Pleasant Surprise After Another”

Rita Possehl and her companion Teryl Springstead visited our Issels® Medical Center in Tijuana unsure of what to expect. The two were so satisfied with their experience that they wanted to share their recommendation with other potential patients.

“Caring and Considerate Staff”

One thing that immediately struck Rita and Teryl was the frequency of visits from staff members. The doctors stopped in at least once a day, and other staff members wore name tags and announced themselves each time they entered the room.

Ironically, it can sometimes be a challenge to get rest in a hospital room due to round-the-clock visits for vital sign checks. At Issels®, the checks begin around 8:00 AM and end around 10:00 PM so you can enjoy uninterrupted sleep.

“We Felt Pampered”

Rita and Teryl were impressed by how the staff worked to accommodate the wishes of both. For instance, the women were amazed to discover that Teryl’s dietary preferences were also honored along with Rita’s.

At the end of their stay, Rita and Teryl were pleased with the “warm, friendly staff” and “wholesome, delicious food” and recommended Issels® to other medical companions.

Quality Care at a Comfortable Location

Contact us to learn more about immunotherapy for cancer at our Issels® Medical Center in Tijuana, Mexico.

What Makes the Issels Immunotherapy Approach So Different?

Each Person is Different, and as a Result, so is Every Treatment Plan!
Each Person is Different, and as a Result, so is Every Treatment Plan!

Choosing a cancer treatment program can be the most important decision you’ll ever face. What makes the Issels® immunotherapy for cancer approach so different from traditional forms of cancer treatment?

Issels® Treatment Programs Are Individually Developed

Regardless of the type of cancer, each patient’s experience is unique. Our treatment programs are personally tailored to address a patient’s specific needs.

Issels® Therapies Are Created from a Patient’s Own Immune Cells

Issels® immunotherapy protocols boost your body’s immune response to use the power of your own natural defense mechanisms.

Issels® Immunotherapy Has No Adverse Side Effects

Immunotherapy is non-toxic and has less risk of side effects than traditional cancer treatments such as chemotherapy and radiation. Our immunotherapy programs should also be distinguished from pharmaceutically-developed immunotherapy drugs, which can trigger serious negative reactions.

Issels® Immunotherapy Programs Are Comprehensive

Focusing cancer treatment on one form can limit its impact on the disease. Our immunotherapy programs integrate a number of complementary elements that work together for greater effectiveness.

Issels® Treatment Programs Focus on Cancer and Its Environment

Destroying cancer cells is only part of the process. Our immunotherapy for cancer is also directed at altering the internal environment that promotes tumor growth.

Issels® Immunotherapy Is Not a Trial

Patients who participate in clinical trials may end up receiving a placebo. Our cancer vaccines and gene-targeted therapies have stood the test of time.

Experience the Issels® Difference

Want to learn more? Visit our website to read and hear testimonials from patients who have achieved years and decades of recurrence-free remission thanks to our Issels® immunotherapy for cancer programs.

John McCain and Glioblastoma

It's Time to Stop Cancer
It’s Time to Stop Cancer

Two years ago, then-Vice President Joe Biden was inspired by the death of his son to launch a “moonshot” campaign for cancer treatment research. Today, Sen. John McCain’s battle against brain cancer has once again turned a spotlight on the disease.

Vice-President Biden Joins the Fight Against Cancer

In May 2015, Biden’s eldest son Beau succumbed to glioblastoma, an aggressive form of brain cancer. The same disease claimed the late Sen. Edward Kennedy in 2009.

Four months after his son’s death, Biden called off his expected run for the presidency in order to launch a campaign of a different sort. Biden and his advisors joined forces with the American Association for Cancer Research to ramp up the search for a cure.

Brain Cancer Remains in Public Awareness

Arizona Sen. John McCain, a one-time Presidential candidate himself, was diagnosed with glioblastoma this past July. The diagnosis added another layer of drama when McCain returned to Washington, D.C. a week later and cast the deciding vote against a proposed repeal of the Affordable Care Act.

Last month, McCain appeared on CNN’s State of the Union to discuss his illness. The senator told host Jake Tapper that he would be undergoing an MRI the following day, adding that advancements in cancer treatment gave hope for his prognosis.

State-of-the-Art Immunotherapy from Issels®

Researchers have been making astounding breakthroughs in cancer treatment. Issels® has long been a leader in the use of personally tailored immunotherapy programs to successfully treat patients with all forms of cancer.

Contact us for more information about our integrative, non-toxic treatments such as cancer vaccines and NK cells.