Molecularly Targeted Therapy Emerges As Another Possible Cancer Treatment

Molecularly Targeted Therapy Emerges As Another Possible Cancer Treatment
Molecularly Targeted Therapy Emerges As Another Possible Cancer Treatment

The problem with traditional cancer treatments is that they attack healthy cells along with diseased cells, which results in serious side effects such as fatigue and hair loss. Doctors are encouraged by the success of a new cancer treatment that zeroes in on the cancer cells.

The “Next Revolution in Cancer Therapy”

Molecularly targeted therapy is being hailed as the next big step in cancer treatment. These new drugs are designed at the molecular level to attack the diseased cells of a specific type of cancer. In addition, they can identify specific molecules that are part of specific cancers.

The drugs are created by a process that is the reverse of how most cancer drugs are developed. Scientists identify an abnormal molecule that’s unique to a particular type of cancer, then design a drug that shuts down its activity.

Gleevec: Paving the Way

Novartis Pharmaceuticals has developed Gleevec, also known as STI571, which is leading the way for molecularly targeted therapy. Gleevec is used for chronic myeloid leukemia, or CML, which is a rare form of the disease characterized by excessive production of white blood cells.

Researchers discovered that Gleevec is also effective against GIST, a rare gastrointestinal cancer. GIST features a unique enzyme related to the original target enzyme in CML.

State-of-the-Art Cancer Treatment at Issels®

Gene-targeted therapies, including Gleevec, Tamoxifen and Avastin, are a significant part of our personalized treatment programs. Issels® also uses non-toxic immunotherapy treatments that boost the immune system’s ability to target tumor cells.

Contact us today for more information about our decades of success in helping patients achieve long-term remission.

Cancer Treatment: Foods to Avoid While in Treatment

Cancer Treatment: Foods to Avoid While in Treatment
Cancer Treatment: Foods to Avoid While in Treatment-

When you undergo cancer treatment, chances are good that side effects such as nausea and mouth sores will cause your taste buds to change. Your overall health can also be affected by the nutritional choices you make.

Many types of cancer treatments can weaken your immune system, even after they’re over. As a result, your body is vulnerable to food-borne bacteria and viruses that otherwise might not affect you.

Here are foods you should avoid during and after treatment to reduce the risk of food poisoning, even if they haven’t caused problems in the past.

Proteins

– Smoked fish

– Raw or undercooked beef and seafood, including sushi and sashimi

– Raw, unpasteurized eggs and items such as raw cookie dough that are made with raw eggs

– Undercooked eggs, including soft-boiled, over-easy and poached

– Soft cheeses made from unpasteurized milk, such as Brie, feta and goat cheese

– Deli salads made with chicken, eggs, seafood or ham

– Cold hot dogs or cold deli meat, which should always be cooked until steaming hot

– Refrigerated paté

Produce

– Fresh fruits and vegetables that have not been washed

– Unpasteurized fruit juice or cider

– Raw sprouts

If you’re uncertain about any food items, don’t take chances. Talk to your healthcare team before consuming any questionable products.

Personalized Cancer Treatment from Issels®

Our individually tailored treatment programs are designed to boost the effectiveness of your body’s immune system. In addition, our immunotherapy doesn’t have the debilitating side effects that often accompany traditional forms of cancer treatment.

Contact us for more information about our cancer vaccines and other treatments we have been successfully using for decades.

Tumor Suppressing Protein May Lead to New Pancreatic Cancer Treatments

Tumor Suppressing Protein May Lead to New Pancreatic Cancer Treatments
Tumor Suppressing Protein May Lead to New Pancreatic Cancer Treatments

While a protein known as p53 has long been recognized as a potent factor in suppressing tumors, the reasons have been unclear. Scientists are now discovering more about p53, including the existence of a “super” version, that may have valuable implications for cancer immunotherapy.

Finding the Right Balance

Balance is essential for realizing the maximum benefits of p53. Too little leaves the door open for tumor growth, but too much can cause developmental problems.

A research team at the Stanford University School of Medicine tested a variety of p53 mutations on mice that were susceptible to pancreatic cancer. The scientists were surprised to find that one version of the protein kept the mice tumor-free for longer periods of time.

A “Supercharged” Tumor Suppressor

According to Dr. Laura Attardi, senior author of the study, the mutated protein hit a “sweet spot” that allowed embryos to develop without any problems and gave adult mice greater resistance to tumors. The mutation appears to hyperactivate the p53 protein, causing it to affect a number of downstream targets.

With hundreds of genes impacted by p53 activity, Attardi’s team turned to the question of discovering which ones were involved in tumor development. They discovered the pathway of three proteins, led by p53, that created a chain reaction preventing development of tumor cells.

Issels®: Leading the Way in Cancer Immunotherapy

Our personalized immunotherapy programs include gene-targeted therapies that shut down specific molecules required for cancer growth. Treatments are integrated with other therapies that combine for the most effective ways of fighting tumor cells.

Contact us to learn more about our success in helping patients achieve long-term remission

Why Many Breast Cancer Patients Stop Treatment or Only Take Partial Treatment

Why Many Breast Cancer Patients Stop Treatment or Only Take Partial Treatment
Why Many Breast Cancer Patients Stop Treatment or Only Take Partial Treatment

Many women do not trust the health care system and will often forgo radiation and drug therapy after breast cancer surgery. That is according to a survey of 2,700 breast cancer patients by researchers at Johns Hopkins University. Lead author of the survey, Lorraine Dean, said over 30 percent skip treatments that are intended to kill any cancer cells that remain after surgery.

Contact Issels® for information on how combining conventional treatments with immunotherapy cancer treatment reduces the likelihood of relapse.

Doctor-patient trust is crucial

Cancer is a devastating disease and it is understandable that patients experience feelings of helplessness. It’s not just women with breast cancer who are losing trust in doctors and the health care system, it’s the general public as well. People often feel that doctors put their own financial interest ahead of patient care. When patients feel their doctors don’t listen to them or take their concerns seriously, trust begins to erode.

For the best possible outcome, it is necessary that doctors and patients have a strong bond of trust. Patients should feel comfortable being fully honest with health care providers and the doctors should always remember that a patient’s trust in them is a vital and necessary component of proper medical care. Each person’s cancer is unique and treatment should be based on the specific needs of each patient.

Personalized cancer treatment

At Issels®, we have been practicing individualized treatment for more than 60 years. We want you to make informed decisions about your cancer treatment options. Contact us today for more information on our autologous (from the patient’s own blood) non-toxic cancer treatment protocols.

Cancer Treatment: Food Safety Tips After Treatment

Cancer Treatment: Food Safety Tips After Treatment
Cancer Treatment: Food Safety Tips After Treatment

Even after successful cancer treatment, your body is not at full strength. It may be more difficult for your immune system to fight foodborne illness than it was before treatment.

Use these tips to reduce the risk of food poisoning both during and after immunotherapy and other cancer treatment programs.

1. Practice “Safe Shopping”

– Don’t buy food products stored or displayed in areas that appear unsanitary.

– Don’t buy produce with bruises or other visible damage.

– Don’t buy cans that are dented or showing bulges.

2. Follow Careful Prep and Clean-Up Methods

– Rinse and dry all fresh fruits and vegetables.

– Wipe the tops of cans thoroughly before opening.

Wash hands with soap and hot water for at least 20 seconds before and after prep. Use the same method to clean all dishes and utensils.

– Disinfect cutting boards and kitchen surfaces using a mixture of one teaspoon of unscented liquid bleach with a quart of water.

3. Watch Food Temperatures

– Always use a food thermometer with meat and poultry to make sure products are sufficiently cooked.

– Perishable foods should be refrigerated or frozen within two hours of buying or cooking, and even more quickly during periods of hot weather.

– Thaw frozen food in the refrigerator and cook immediately afterwards.

Nutritional Immunotherapy at Issels®

Scientists have found a link between poor nutrition and cancer development. Our individualized cancer treatment programs include methods to restore nutritional balance and promote optimum functioning of the immune system.

Contact us to learn more about nutritional immunotherapy and other integrative immunotherapy programs at Issels®.

 

Breast Cancer Patients Treated with Combination Drugs Suffer More Side Effects

New Research for Breast Cancer Studies Genes
New Research for Breast Cancer Studies Genes

One of the concerns with traditional cancer treatment is the range and severity of potential side effects that may occur. Based on the results of a recent study, patients with advanced breast cancer who are treated with a certain combination of drugs are at greater risk for serious side effects.

Fighting Cancer on Two Fronts

Some breast cancers are classified as “hormone receptor-positive.” Signals from hormones such as estrogen and progesterone reach receptors in the cancer cells, triggering further growth. Patients are commonly treated with a receptor blocker such as tamoxifen in conjunction with drugs that specifically target molecules involved in cancer cell development.

Previous research indicated that this combination therapy enabled patients to live longer without progression of the tumors. The missing piece of the puzzle was the extent to which treatment could cause side effects.

Evaluating Side Effects of Combination Therapies

A study conducted by an international research team found that patients with combination therapy were more susceptible to side effects such as fatigue, diarrhea and hyperglycemia. The degree of risk varied based on the particular drugs involved.

Scientists plan to use these results to design courses of treatment that are less likely to produce side effects. In the meantime, since these therapies do have benefits, doctors will have more information to use in prescribing and managing combination drug treatments.

Issels® Leads the Way with Non-Toxic Cancer Treatment

Personalized cancer treatment at Issels® uses a patient’s own immune cells, reducing the risk of of debilitating side effects. Contact us to learn more about our cancer vaccines and other innovative treatment programs.

Individualized Cancer Treatment