Tag Archives: Advanced Cancer Treatment

Immunotherapy and Its Use in Stage 2 and 3 Cancers

There is New Hope for Cancer Patients. Don't Give up!
There is New Hope for Cancer Patients. Don’t Give up!

Immunotherapy drugs have become a valuable weapon in the fight against metastatic cancer, also known as Stage 4. Researchers are discovering that immunotherapy for cancer treatment can also have positive results when used during earlier stages of the disease.

Immunotherapy and Early-Stage Cancer

At the recent European Society for Medical Oncology (ESMO) congress in Madrid, AstraZeneca presented successful trial results for its immuno-oncology drug Imfinzi in treating mid-stage lung cancer. AstraZeneca is considered a latecomer to the I-O field as compared to established companies such as Merck and Bristol-Meyers Squibb.

For their part, Bristol-Meyers produced evidence regarding Opdivo, the company’s widely used late-stage I-O drug. Opdivo has been shown to prevent relapses in melanoma patients when administered immediately post-surgery.

Supplementing Surgery with Immunotherapy

This method of following surgery with cancer treatment is referred to as adjuvant therapy. With the success of Opdivo, a number of trials are being conducted on adjuvant therapy using I-O drugs with a range of cancer types. Some trials are even focusing on neoadjuvant, or pre-surgery, treatment for breast, neck and head cancers.

What’s Next?

If the trend of early-stage immunotherapy treatment continues, early detection becomes even more important than ever. According to Pascal Soriot, CEO of AstraZeneca, effective early treatment is a powerful incentive for increased use of screening methods.

Non-Toxic Immunotherapy Programs from Issels®

Our cancer vaccines and other non-toxic, personally tailored immunotherapy treatment programs have resulted in long-term remission for patients with all types of therapy-resistant cancers. Contact us for more information about Issels®, the leader in immunotherapy for cancer treatment.

NCI Studies Disparities in Cancer Treatment in Rural Communities

If You and Your Family Does Choose to Live Out in the Country, Make Sure You Live Close to a Location with Good Healthcare Providers.
If You and Your Family Does Choose to Live Out in the Country, Make Sure You Live Close to a Location with Good Healthcare Providers.

Does where you live affect your chances of surviving cancer? Recent studies are putting a focus on the disparities of cancer treatment between rural and urban communities.

Equal Access to Health Care?

Overall, cancer death rates in the United States have declined over the last 40 years. Unfortunately, two studies from the National Cancer Institute and Centers for Disease Control have revealed that cancer death rates are higher in rural areas and declining at a much slower pace.

NCI has a history of promoting cancer control in Appalachia, with efforts directed at prevention and early detection. Issues surrounding last year’s presidential election have further raised the visibility of questions about access to quality health care.

As research methods and tools become more sophisticated, scientists have the advantage of more granular data. This allows for more detailed plotting of disease patterns and trends as they apply to specific geographic regions.

Healthcare Organizations Rise to the Challenge

Growing acknowledgement of the problem is also raising the sense of urgency. Researchers at the University of Washington found that differences in life expectancy by county are large and growing even larger.

NCI, along with federal agencies such as the Centers for Medicare and Medicaid Services, are joining forces to collaborate on research and implementation. The next big step is a May 2018 meeting that NCI is convening among major organizations in the cancer community.

Issels®: Accessible and High-Quality Cancer Treatment

Our integrative immunotherapy programs incorporate multiple elements to create the best possible treatment for your particular diagnosis. Contact us for more information about cancer vaccines, NK cells and other non-toxic treatment methods.

New Guidance on Lymph Node Removal for Melanoma Patients

New Guidance on Lymph Node Surgery
New Guidance on Lymph Node Surgery

Aggressive surgery has often been the preferred approach for patients in whom melanoma has spread to the lymph nodes. Results of a recent trial suggest that a conservative treatment of watchful waiting may actually be more beneficial.

Is Completion Surgery Necessary?

Once a patient is diagnosed with melanoma, the traditional procedure has been to conduct a sentinel lymph node biopsy. If cancer cells are detected, the next step is usually immediate removal of the remaining regional lymph nodes in the surrounding area.

Surgery vs. Watchful Waiting

MSLT-II involved 1,934 participants who had been diagnosed with skin melanoma of medium thickness that had spread to sentinel lymph nodes but nowhere else in the body. Half underwent immediate lymph node removal surgery while the other half were monitored for signs of cancer in the regional lymph nodes.

After three years, 86 percent of patients in each group had not succumbed to melanoma. In addition, 68 percent of the surgery group and 63 percent of the monitored group had not experienced any recurrence of cancer.

Greater Risk of Complications

While difference in recurrence rate was negligible, the surgery group was found to be far more susceptible to complications. Those patients were approximately four times more likely to experience lymphedema, which is a buildup of excess lymph fluid that causes swelling.

Immunotherapy for Cancer: State-of-the-Art Treatment

We have successfully treated patients with melanoma and other forms of cancer in both early and late stages. Contact us to learn more about Issels® and our individually developed, non-toxic immunotherapy for cancer programs.

Taking Care of Yourself: Important Safety Reminders About Your Cancer-Compromised Immune System

Keep in Mind Your Immune System

When you’re undergoing cancer treatment, it demands the full attention of your immune system, leaving the door open for bacteria and other germs to sneak in. Use these food-handling tips to reduce the risk of disease and infection.

Food Preparation

  • Wash hands thoroughly with warm, soapy water before and after food prep and before eating.
  • Keep foods at the proper temperature. Hot foods should be above 140° F, while cold foods should be below 40° F.
  • Don’t thaw proteins at room temperature. Use a microwave or place them in the refrigerator with a pan to catch drips.
  • Defrosted foods should be used right away and never refrozen.
  • Don’t take chances. If any foods look, feel or smell strange, dispose of them immediately.
  • Wash produce under running water using a vegetable scrubber. Don’t use soaps, bleaches or other chemical cleaning products.

Cooking

  • Always use a clean spoon when tasting foods while cooking.
  • Don’t guess when cooking meat. Use a food thermometer for accuracy. Beef should be cooked to 160° F while poultry should be cooked to 180° F.
  • If your microwave doesn’t have a turntable, rotate the dish a quarter-turn a couple of times during cooking to ensure that food is evenly heated.
  • When reheating leftovers, cover food with a lid or plastic wrap and stir frequently.

Immunotherapy at Issels®: Personalized Non-Toxic Cancer Treatment

Our immunotherapy treatment programs are designed to boost your immune system, allowing it to fight cancer naturally. Visit our website to learn more about how our state-of-the-art cancer treatment has helped many patients achieve long-term remission.

July is Bladder Cancer Awareness Month, Will You Be Wearing the Yellow Ribbon?

New Immunotherapy Drug Can Help Fight Bladder Cancer
New Immunotherapy Drug Can Help Fight Bladder Cancer

If you or someone you love has received a diagnosis of bladder cancer or is in stage four and have exhausted treatment options, NBC news reports that there may be new hope for immunotherapy treatment for bladder cancer. This information is timely as July is Bladder Cancer Awareness Month.

Immunotherapy treatments

Immunotherapy for bladder cancer works by treating a person’s immune system so it has the ability to fight cancer.

According to the NBC news article, “more successful approaches, involve training immune cells to recognize a patient’s specific tumors, or finding and amplifying a patient’s own tumor-specific immune cells.” Immunotherapy now appears to be the best course of cancer treatment for many patients.

New drug, new hope

Hope now lies in a drug newly-approved by the FDA called atezolizumab (brand name Tecentriq) that boosts the immune system to slow the spread of tumors in patients in the advanced stages of bladder cancer. It’s the latest development in immunotherapy for bladder cancer treatments and it has shown promising results.

In a study of 119 patients who received the drug as treatment revealed that growth stopped in the tumors in 24% of those patients in the advanced stages of bladder cancer. The drug also shrank the tumors by 30%. According to the research team, 21 of the original patients from 2014 who received the immunotherapy for bladder cancer are still in remission today.

Learn more about our non-toxic immunotherapy for bladder cancer by contacting Issels® Integrative Immuno-Oncology.

New Regulators That Impact Cell Growth Are Discovered and May Impact Cancer Growth

Regulated Cell Growth
Regulated Cell Growth

A new discovery made at the Center for RNA Research at IBS could provide some insight into how cancerous tumors are formed in the body and how their growth can be repressed. This could be very big news for those undergoing treatment with Issels Integrative Immuno-Oncology.

For the first time, researchers have discovered that the enzyme PKR is activated during cellular mitosis. PKR was previously known as a trigger of immune response during a viral infection. It is believed that the disruption of PKR activation causes a delay in mitotic progression and defects in cell division that ultimately results in cancer growth.

Researchers also discovered that PKR activation is closely regulated by TAR RNA Binding Protein, or TRBP. TRBP inhibits PKR activation and otherwise helps control the cell cycle.

It isn’t yet known what this new research means for cancer treatment, but this new discovery could lead to revolutionary new cancer treatments that prevent cancer cells from dividing. Given time, there could be a treatment that safely affects tumors before they have time to spread.

Issels® and Cancer Treatment

We at Issels® focus closely on the tumor and the tumor microenvironment in our cancer treatment and research, so this discovery is very exciting and could change the way we look at cancer treatment. For more information about Issels® and our alternative cancer treatments, visit us online at http://issels.com.