Tag Archives: Alternative Cancer Treatments

Targeting Proteins May Prevent Metastasis of Cancers

Targeting Proteins May Prevent Metastasis of Cancers
Targeting Proteins May Prevent Metastasis of Cancers

New research has uncovered the existence of a protein that helps tumors spread, enabling their capacity to grow blood vessels. Could targeting this protein in cancer treatment experimentation lead to a new potential cure?

Not So Fast!
Published in the journal Oncogene, the study involved laboratory experiments blocking the protein latent TGF-beta binding protein 3 (LTBP3), prevented tumors from effectively metastasizing. A collaborative effort between multiple researchers, the investigation began based on the observation that lower levels of the protein LTBP3 correlated to an improved survival outcome in those with certain types of cancer.

A Complex Dynamic
The LTBP3 protein binds to a substance called TGF-beta to metastasize. TGF-beta presents a double-edged sword, either aiding the spread of tumors – or putting a halt to metastasis. Our bodies rely on TGF-beta to function properly. In early stages, it suppresses cancer growth. However in advanced cancers, it transforms and promotes tumor growth. The cancer treatment trick? To control the harmful effects of TGF-beta without disturbing normal cell function.

A Confirmed Association
As researchers looked closer into the interplay of LTBP3 and TGF-beta using head and neck carcinoma and fibroscarcoma in mice and chicks, the scientists discovered LTBP3 helps tumors grow blood vessels, and primary tumors could not metastasize properly in its absence. This corroborated the previous research associating lower levels of the LTBP3 protein with better patient outcomes. Further research into this complex dynamic is highly anticipated.

Looking for a more targeted cancer treatment plan? Issels® unique, highly-personalized cancer treatment protocols are clinically-proven, scientifically-backed, and compatible with both traditional and alternative treatment therapies. Learn more about the Issels® immunotherapy difference today.

PBS News Hour Features Immunotherapy for Cancer

Diverse Hands Holding The Word Cancer
Immunotherapy brings breakthroughs to cancer treatment.

As immunotherapy for cancer becomes an increasingly valuable method for fighting tumors, stories have moved from medical journals into the mainstream media. Immunotherapy was the topic of a recent edition of Leading Edge, a weekly science and technology report featured on PBS News Hour.

Immunotherapy: One Woman’s Story

First up were Melinda Welsh, a journalist who was diagnosed with squamous cell carcinoma, and her oncologist, Dr. Alain Algazi of the University of California, San Francisco. When Melinda’s cancer metastasized, her doctors told her she had no more than a year to live.

Dr. Algazi began treating Melinda with an immunotherapy method known as a checkpoint inhibitor, which releases the “brakes” that prevent the body’s immune system from attacking tumor cells. Melinda then went into remission and continues today, three years after receiving her original diagnosis.

The Immunotherapy Difference

Host Hari Sreenivasan then conducted a discussion with Dr. Jeffery Bluestone, CEO of Parker Institute for Cancer Immunotherapy, and New York Times reporter Matt Richter.

Highlights of the conversation include:

Immunotherapy for cancer differs drastically from other treatments in that it uses the body’s natural power rather than poisons to fight tumors.

• Richter, who has profiled a number of cancer patients, characterized immunotherapy as a “quantum leap” in the fight against cancer.

• Dr. Bluestone cited the example of melanoma, which has gone from 5 percent five-year survival to 40 percent five-year survival.

A Personalized Approach

Our non-toxic immunotherapy for cancer treatments are tailored to meet your specific needs. Visit our website to read and hear success stories from patients who have been treated at our Issels® clinics.

Higher Vitamin D Levels May Boost Breast Cancer Survival

Higher Vitamin D Levels May Boost Breast Cancer Survival
Higher Vitamin D Levels May Boost Breast Cancer Survival

Vitamin D has long been known as an essential nutrient that aids your bones with calcium absorption. A recent study shows that there may also be a link between vitamin D levels and surviving breast cancer.

Examining the Link between Vitamin D and Breast Cancer Survival

The study, performed by a research team from the Roswell Park Cancer Institute in Buffalo, began in 2006 with a group of women from California who had been diagnosed with invasive breast cancer. Participants were divided into three sub-groups based on blood levels of a particular vitamin D marker.

Women with more advanced cancers tended to have low levels of the marker. Over an average of seven years of follow-up, 100 of these women died compared to 76 women with high levels. There were approximately 1,600 women total involved in the study.

In addition, women with the highest vitamin D levels were 28 percent less likely to die of any cause, once factors such as tumor characteristics were accounted for. This link was the strongest among pre-menopausal women.

What Does This Mean for the Future?

According to lead author Song Yao, overall results showed “30 percent reduction of all-cause mortality” linked to vitamin D levels at the time of diagnosis. While the study supports previous research linking vitamin D with breast cancer survival, Yao said a randomized controlled trial would be needed to determine a direct cause-and-effect.

Immunotherapy for Cancer: Going Beyond Traditional Treatments

Immunotherapy for cancer has been gaining a lot of attention recently, but at Issels® we have a decades-long history of using these state-of-the-art methods successfully. Contact us for more information.

Cancer Survivors: A Unique Perspective on Hope

Cancer Survivors: A Unique Perspective on Hope
Cancer Survivors: A Unique Perspective on Hope

Here at Issels®, we frequently encounter people who have been newly diagnosed with cancer, and their hope for a long healthy life seems gone. For the longest time, a cancer diagnosis has been linked with impending death, and while it’s true that some do lose their lives to this terrible disease, for the first time cancer patients can truly have hope.

There have been many advances in cancer treatment in recent years, and more patients are getting screened early on if they feel they are at higher risk. Early detections and improvements in treatment are saving lives, and the number of cancer survivors is expected to increase at an incredible rate in the months and years ahead. Currently, there are 15.5 million cancer survivors in the United States, and in just ten years that number is expected to hit 20 million.

Knowing these numbers is important, because cancer survivors have different needs than cancer patients; especially those who have undergone treatments such as chemotherapy and radiation. These patients often have serious, long-standing effects from what we’ve always thought of as “conventional” cancer treatments, and experts are still trying to find a way to help them with the physiological and psychological effects that can last the rest of their lives.

There’s no question that chemotherapy and radiation have been life-saving for many cancer survivors. However, they have also caused significant problems, such as heart disease, osteoporosis, neuropathy, and other physical ailments.

At Issels®, our focus is on immunotherapy, which has been shown to have no devastating long-term effects. Please contact us to learn more about this breakthrough in cancer treatment.

Immunotherapy for Cancer – Is It Right for You?

Could Immunotherapy Be Your Miracle Treatment?
Could Immunotherapy Be Your Miracle Treatment?

The concept of using your body’s own resources to fight cancer dates back more than 100 years, but immunotherapy for cancer has recently emerged in the public eye thanks to incredible advancements over the last 10 years. Is this cutting-edge treatment right for you?

Functions of the immune system

Traditional cancer treatments, such as radiation and chemotherapy, have focused on fighting tumors from the “outside.” Immunotherapy is different because it involves boosting your immune system’s ability to attack cancer cells naturally.

Your immune system operates much like an army, with each cell having a specific duty that contributes to the overall function.

• Cells on the “front line” recognize foreign bodies that have entered your system.

• Other cells take on the actual “battle” of attacking and defeating those invaders.

• “Messenger” cells tie everything together by facilitating communications between the cells.

How immunotherapy helps your body fight cancer

Cancer presents a unique challenge for this normally efficient process. Since cancer cells develop from your body’s own cells, the immune system has difficulty recognizing them, which gives these mutated cells a chance to multiply.

Immunotherapy for cancer involves complex interactions, but they generally fall into one of two categories. Some treatments make cancer cells more identifiable to your immune system. Others boost your system’s immune response, which includes actions such as blocking certain factors that enable growth of a tumor.

Our Issels® center has been successfully using immunotherapy for cancer for more than 60 years. Visit our website to read and watch testimonials from patients of all ages who have benefited from our personalized non-toxic treatments.