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Ultraviolet Blood Irradiation Therapy

Ultraviolet Blood Irradiation, also called Photoluminescence Therapy, is intravenously applied ultraviolet energy. Due to its profound photochemical, biochemical and physiological effects it has been of great value in a wide variety of diseases according to abundant literature over a time period of 100 years.

Niels Ryberg Finsen is considered the father of Ultraviolet Blood Irradiation. In the late 1890s, he treated various skin conditions with Ultraviolet Blood Irradiation and he and his successors reported a success rate of about 98% with lupus vulgaris, a tuberculosis-like disease of the skin and mucous membranes. In 1903 he was awarded the Nobel Prize for his photochemotherapy.

In the 1930s, 1940s and 1950s, E. K. Knott, M.D. in Seattle, Washington, and other physicians applied this treatment successfully with a variety of conditions, such as bacterial diseases, viral infections including acute and chronic hepatitis, poliomyelitis, encephalitis, overwhelming toxemias, rheumatoid arthritis and many others.

In Europe, since the early 1950s, Josef M. Issels, M.D. administered Ultraviolet Blood Irradiation, or Photoluminescence Therapy, as one important component of his treatment program to thousands of his patients suffering from cancer and various immune disorders.

The impairment of cell respiration by oxygen deficiency has been found to be a major contributing factor in the development of these diseases. The research work of Nobel Laureate Otto Warburg, and other researchers such as William F. Koch, has proved that in malignant diseases the oxidation process in cells is blocked and energy is produced by fermentation. In such conditions micro-organisms that lived in symbiosis with the host organism may become pathogenic and parasitic. When oxygenation is restored, these micro-organisms can revert to the non-pathogenic state.

Ultraviolet energy has been known to inactivate viruses while preserving their ability to be used as antigens in the preparation of vaccines. It has also shown to modulate the immune response by changing the antigenic structure in blood cells.

Most important for cancer therapy is the observation that controlled ultraviolet energy exposure promotes the maturation of dendritic cells through oxidative stimulation. This effect is similar to that of the oxygen/ozone action, and is very important as the immune system’s dendritic cell fraction plays a key role in the fight against cancer. Other cells of the immune system are activated as well, along with the enhanced production of cytokines, such as IL-2, tumor necrosis factor and interferon.

In addition, researchers discovered the following beneficial reactions to Ultraviolet Blood Irradiation:

  • Inactivation of toxins;
  • Destruction and growth inhibition of bacteria;
  • Vasodilation;
  • Activation of steroid hormones;
  • Increase in the oxygen combining power of the blood and oxygen transportation to organs;
  • Decrease of blood viscosity by stimulation of fibrinolysis;
  • Improvement of blood circulation;
  • Stimulation of corticosteroid production; and
  • Decrease of platelet aggregation.

The technique of Ultraviolet Blood Irradiation is the following:

A certain amount of venous blood is withdrawn by venipuncture and exposed twice to a controlled amount of UV-A light in a joint circuit inside a UV-A light permeable quartz chamber, before it will be returned to the patient. The number of treatments depends on individual needs.


DISCLAIMER: The extent of the response to treatment varies from patient to patient, even with similar diagnosis as the internal bodily environment is unique to each individual patient.

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Last updated: 5/11/2009
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