Tag Archives: Avoiding Cancer

Cancer Research

Norwegian Research Finds a 16% Drop in Cancer Rates Later in Life Among Those Taking Blood Thinners

Are You Taking Blood Thinners? Research Shows Your Risk for Cancer is Lower
Are You Taking Blood Thinners? Research Shows Your Risk for Cancer is Lower.

Blood thinners such as Warfarin are prescribed for millions of people around the world to control a range of cardiovascular problems. Based on the results of a recent study, the drugs may also reduce the risk of cancer, which could have future implications for cancer treatment.

A Surprising Weapon in the Battle Against Cancer

The study, recently published in JAMA Internal Medicine, involved 1.25 million people over the age of 50 in Norway. Researchers at the University of Bergen found that those who took Warfarin were 16 percent less likely to develop cancer than those who didn’t.

Benefits were even more pronounced for three of the most common forms of cancer. Prostate cancer had the highest risk reduction at 31 percent, followed by lung cancer at 20 percent and breast cancer at 10 percent.

The good news doesn’t end there. Patients taking Warfarin for atrial fibrillation, an abnormal heart rhythm, saw a 29 percent reduction in risk for bowel cancer.

Blood Thinners: A Form of Immunotherapy?

At this point, researchers are unclear how Warfarin affects the risk of cancer. They believe that the drugs may inhibit the signaling power of cancer cells, leaving them vulnerable to attack from the body’s immune system.

Despite the promising results, medical experts warn against self-medicating with Warfarin. The drug can have serious side effects, so it should always be taken under a doctor’s supervision.

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High Fat Diets Are Linked to Colon Cancer

High Fat Diets Are Linked to Colon Cancer
High Fat Diets Are Linked to Colon Cancer

Doctors regularly warn patients that obesity is linked to an increased risk of cancer. A study by researchers at MIT has shed some light on how high-fat diets can trigger colon cancer.

The Role of Stem Cells in Colon Cancer

Colon cancer arises from mutations that tend to accumulate among intestinal stem cells, which last a lifetime. Omer Yilmaz, an assistant professor of biology at MIT, led a team that set out to discover the process behind these cellular changes.

For nine months to a year, Yilmaz and his team fed healthy mice a diet composed of 60 percent fat. In addition to gaining up to 50 percent more body mass, these mice developed more intestinal tumors than those on a healthy diet.

Effects of High-Fat Diet on Intestinal Cells

Researchers observed significant changes in the intestinal stem cells of the mice:

  • The mice eating a high-fat diet had a higher number of intestinal stem cells. In addition, they were able to operate free of input from niche cells that normally regulate stem cell activity.
  • Progenitor cells, which are differentiated “daughters” of stem cells, began to take on characteristics of stem cells, including longer life span and ability to generate mini-intestines outside the body.

Yilmaz is hopeful that, with further investigation, this information will lead to identifying new methods of cancer treatment for obesity-related tumors.

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Cancer Research, News

World Cancer Research Fund: Your Weight Does Impact Cancer Risk

Maintaining a Healthy Weight Reduces Cancer Risk
Maintaining a Healthy Weight Reduces Cancer Risk

Maintaining a healthy weight is beneficial mentally and emotionally as well as physically. Excess weight is linked to diabetes, cardiovascular disease and many other serious health problems. In addition, statistics show that obesity presents the strongest cancer risk of any lifestyle factors.

The Link between Cancer and Lifestyle

According to the World Cancer Research Fund, 20 percent of cancer cases in the United States are at least partially attributable to one or more of these lifestyle factors:

  • Obesity
  • Lack of physical activity
  • Excessive alcohol consumption
  • Inadequate nutrition

Out of these four elements, excess body weight contributes to 20 percent of all cancer-related deaths.

How Excess Weight Affects Cancer Risk

Excess body fat creates a number of imbalances that can lead to the development or growth of cancer cells, such as:

  • Interference with the immune system response
  • Skewed levels of hormones, as well as the proteins that help the body process them
  • Improper levels of substances that control cell growth

Does Weight Loss Help?

While studies regarding weight loss and cancer are still limited, growing evidence suggests that it can reduce the risk of post-menopausal breast cancer and more aggressive forms of prostate cancer. Ongoing tests are examining the relationship between weight loss and other forms of cancer.

The weight per se is not the contributing factor. It’s the physical changes weight loss brings, such as normalizing hormone levels that help reduce cancer risk.

Immunotherapy for Cancer Includes Lifestyle Considerations

Cancer Research, News

Very Hot Beverages Classed as Cancer Causing by WHO

Coffee Is Unlikely To Cause Cancer
Coffee Is Unlikely To Cause Cancer

If you’re a coffee drinker, you’ll be happy to hear that the World Health Organization (WHO) has downgraded coffee as a cancer risk. But make sure you’re not drinking it at excessively high temperatures, as hot beverages are now classified as carcinogens.

Coffee is “Unlikely to Cause” Cancer

WHO’s International Agency for Research on Cancer (IARC), composed of 23 scientists from 10 countries, put coffee on its list of possible cancer risks in 1991, when studies revealed a link to bladder cancer. Modern, more sophisticated tests have shown there is no way to prove a definitive connection.

Further review of current studies has led IARC to conclude that coffee most likely does not cause breast cancer, prostate cancer or pancreatic cancer, while risks of liver cancer and endometrial cancer may actually be reduced. Coffee beans contain antioxidants, which are believed to protect against cancer, but increased consumption of caffeine can lead to other health problems, including insomnia and migraines.

Link between Cancer and Excessively Hot Beverages

Studies of hot beverages focused on consumption of mate, a caffeine-rich tea popular in South America. A link was found between mate and esophageal cancer, but the drink is traditionally served at temperatures above 149°F, while in the United States coffee and other hot drinks are served at lower temperatures.

Immunotherapy for Cancer Fights Bladder, Esophageal and All Forms of Cancer

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Alternative Cancer Treatment, Cancer Research, News

Discovery of Six Molecules that Block Cancer

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Blocking Cancer
Blocking Cancer

In a recently released paper from the University of Kansas, scientists announced they have isolated six molecules capable of blocking the protein HuR. Known as an “oncoprotein” that attaches itself to RNA, the HuR protein enables tumor growth. These findings could potentially lead to new non-toxic cancer treatments like those used by Issels® Integrative Immuno-Oncology. Personalized treatment protocols and immunotherapy are proving to be the best route to a cancer cure.

HuR inhibitors

Researchers have been studying HuR cells for many years. The cancer-building protein is found at high levels in practically every type of cancer. These six molecular needles that the University of Kansas scientists have found in the haystack of human molecules are considered a significant breakthrough in halting cancer stem cells, which are considered the seeds of cancer. According to Liang Xu, associate professor of molecular biosciences and one of the authors of the paper, there were no known HuR inhibitors prior to this discovery.

Potential for a wide array cancer treatments

Xu goes on to say that because HuR has a significant role in so many different types of cancer, the discovery of these proteins holds promise for new cancer drugs in the fight against cancers that attack all areas of the body. HuR and other RNA-binding proteins have been considered untreatable until now. This study, published in ACS Chemical Biology, provides proof of the concept that a new class of cancer drugs can be developed specifically for cancer stem cells.

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